You are currently viewing Hyperbolic Tapering and Other Careful Ways to Come Off a Benzodiazepine

In short: Hyperbolic tapering lowers a medication in steps that are a fraction of the current dose, so the reductions get smaller as the dose gets smaller. The Maudsley Deprescribing Guidelines explain why: at low doses, a small amount of medication is still doing a large share of the work. Other careful methods, such as the Ashton Manual’s crossover taper to diazepam (Valium), liquid formulations, and micro-tapering, share the same essentials: the medication is never stopped abruptly, a physician supervises, a dose can be held when symptoms flare, and the person tapering sets the pace.

What is hyperbolic tapering, and why does it come up whenever people talk about coming off of a benzodiazepine?

Hyperbolic tapering is a way of lowering a medication where each reduction is a fraction of the current dose, not a fixed amount. That means that the steps get smaller as the dose gets smaller. The name comes from the shape of the curve you would draw if you plotted the doses on paper, steep at the top and flattening out as it nears the bottom.

If you take Xanax (alprazolam), Klonopin (clonazepam), Ativan (lorazepam), or Valium (diazepam), and you have started reading about how to stop, you have probably run into the term. You may have also run into people arguing about which tapering method is the right one.

I believe that the argument misses the point. There are several careful ways to come off of a benzodiazepine, and they have more in common than their names suggest. So, why do the steps have to shrink at all?

Equal steps look fair on paper, but they do not feel equal.

A very common taper plan is a straight line. A doctor takes the starting dose, divides it into equal pieces, and removes one piece every week or two until nothing is left. It is tidy, and it fits on a prescription pad.

The same pattern comes up again and again when people describe a straight-line taper. The first several cuts are tolerable, and sometimes they are hardly noticed. Then, somewhere in the lower half of the taper, the same size cut that was easy in the beginning puts the person on the couch for weeks.

They did nothing wrong. While each cut was the same size on paper, each one was a larger share of what was left. The plan was the problem.

A hundred dollars is not always the same hundred dollars.

An analogy that might help is to think about money in the bank. Imagine that you have ten thousand dollars in your account, and I take one hundred dollars out of it. Would you notice? You might not even look at the statement.

Now, imagine that you are down to your last two hundred dollars, and I take the same one hundred. I have just taken half of everything you have. The withdrawal slip looks identical, yet your month does not.

While this is not a perfect analogy, because a nervous system is not a checking account, it shows what goes wrong with equal steps. The last cuts of a straight-line taper are the biggest ones, measured the way your body measures them. A proportional taper measures each step against what is left, not against where you started.

Where does the idea of hyperbolic tapering come from?

The source I point people to is the Maudsley Deprescribing Guidelines. The guidelines explain that the relationship between the dose of a drug and its effect on the receptors in the brain is not a straight line, so at low doses, a small amount of medication is still doing a large share of the work. That is the only sentence about receptors you will get from me today.

The practical conclusion is simple. Reductions are made in proportion to the current dose, so they become smaller and smaller as the total dose comes down. The final steps before stopping may be tiny compared to the first ones.

The same guidelines apply this thinking to antidepressants, gabapentinoids, and the sleep medications known as z-drugs, not only to benzodiazepines. It is a general principle for coming off of a medication that the body has adapted to.

Why am I not going to give you a number?

You may have noticed that I have not said what the fraction should be, or how long to wait between steps. This is on purpose. A number in an article becomes a rule in someone’s head, and a rule is exactly what a nervous system in withdrawal does not follow.

The guidelines offer a starting point for a doctor and patient to work from, and then they say to adjust according to how the person responds. Some people tolerate a quicker pace. Others need steps so small, and so far apart, that the taper takes a year, or two, or longer.

So, the fraction and the interval are decisions to make with your own prescriber, based on your history and your symptoms. What I can give you is the shape. The steps shrink as the dose shrinks, and you set the pace.

Unfortunately, many people are still told to come off in a few weeks.

If you are suspicious of taper advice from doctors, you have good reason. The prescription that caused the dependence came from a doctor, usually with an assurance that the medication was safe to take long term. Then, another doctor announces that it is time to stop, and hands over a two-week schedule.

Detox centers and rehabs often do the same thing, with a discharge date set by an insurance policy. Your nervous system has not read the policy. In 2020, the US Food and Drug Administration (FDA) updated the boxed warning on every benzodiazepine to describe physical dependence and withdrawal reactions, and to call for a gradual taper instead of an abrupt stop.

Stopping a benzodiazepine suddenly, or cold turkey, is dangerous and can cause seizures. Please do not do it, no matter who suggests it.

Call 911 or go to an emergency department if you or someone near you has a seizure, becomes confused or starts to hallucinate, or has thoughts of self-harm. If you are having thoughts of suicide or are in a mental health crisis, you can also call or text 988, the Suicide and Crisis Lifeline, at any time.

When a person struggles near the bottom of a taper, they are sometimes told that it proves they are addicted. It does not. Physical dependence is not addiction. It is the body’s expected adaptation to a medication taken as prescribed, and the answer is a smaller, slower step, not an addiction program.

People who do have an addiction deserve respect and proper medical treatment as well, and they deserve a gradual taper just as much. To be fair to my colleagues, many doctors were never taught how to do any of this. I talked about this subject with Nicole Lamberson in the episode on benzo tapers, dependence, and physician desensitization.

Fortunately, there is more than one careful way down.

Long before the word hyperbolic showed up in taper discussions, the Ashton Manual described a careful approach that is still in wide use. It was written by the late Professor C. Heather Ashton of Newcastle University, from her years of running a benzodiazepine withdrawal clinic. It is a favorite topic of mine, and I have a lot to say about it on this show.

The center of her method is the crossover taper. A person taking a short-acting benzodiazepine is switched, gradually and one dose at a time, to a long-acting one, usually Valium, and then tapers from there. A long-acting drug leaves the body slowly, so the blood level stays steadier between doses, and the tablets come in strengths that allow small reductions.

Professor Ashton’s schedules also slow down and make smaller cuts toward the end, which is the same instinct as the proportional taper. And, she wrote plainly that the person tapering must be in control of the schedule. While I am partial to the crossover taper, it does not suit everyone, and some people do better tapering the medication they already take.

How do you make a step small enough when the tablet will not split any further?

This is a good question, and it is where many tapers get stuck. At the low end of a proportional taper, the step you need may be smaller than any piece you can cut from a tablet with a pill splitter. A crumb of a tablet is not a dose.

The answer is usually a different form of the medication. Some benzodiazepines are made as a liquid, and a compounding pharmacy can prepare a liquid or small capsules in strengths that do not exist on the regular shelf. With a liquid and an oral syringe, a reduction can be a small fraction of a milligram.

This also makes it possible to micro-taper, which means making very small reductions every day or every few days, as an alternative to a larger cut followed by a wait. Some people find the small daily steps easier, and others prefer to cut and hold. Either way, changing the form of your medication is a job for your prescriber and a pharmacist who understands tapering, not a kitchen project.

Holding a dose is not failing.

Every careful method includes the hold. If symptoms flare after a reduction, a short hold is a common first answer: you stay where you are before the next step, and if things do not settle within a few weeks, you talk with your prescriber about what comes next rather than waiting indefinitely. A symptom spike is information that the last step was too large or came too soon.

Many patients believe that pushing through is a sign of strength, and that a hold means they are weak or stalling. A hold is not weakness. Faster is not stronger, and a short hold often protects the progress you have already made, though holds are not always the answer: some people, especially when the medication itself has become toxic to them, do better continuing at a steady pace, and that decision is made with the prescriber, never by stopping suddenly.

The people who have been through it often say this better than a doctor can. Barbara Connolly, PhD, joined me to talk about safe benzodiazepine tapering and the Benzo Warrior community. It is worth a listen if you want to hear about the pace of a taper from the patient community’s side.

The shape matters more than the name.

Hyperbolic, proportional, Ashton, crossover, liquid, micro-taper, cut and hold. These are not rival camps. They are tools, and a good taper often uses several of them at once.

What they share is what matters. The medication is never stopped abruptly, the steps get smaller as the dose gets lower, a physician supervises, and the person taking the medication sets the pace. If the taper is too fast, the doctor must help to slow it down, and if it is going well, patient and doctor may agree to go a bit faster, as tolerated.

Coming off of a benzodiazepine this way takes longer than anyone wants it to. Yet, the nervous system is not broken, and it does recalibrate when it is given time. A slow taper is how you give it that time.

Readers who want help with a taper can contact the office today.

This article is educational. It is not medical advice, and reading it does not create a doctor-patient relationship. Decisions about starting, continuing, or tapering any medication should be made with your own physician.